Maple

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Maple is a high-level programming language used for mathematical computations, symbolic computation, and creating interactive educational tools. It is widely used in fields such as engineering, physics, mathematics, and scientific research.

Hello, world:

> printf( "Hello world!\n" ): # print without quotes
Hello world!

Popularity: Less than 1% of developers are using or have used this language.*
*According to StackOverflow's 2023 survey.